Red blood cell infection caused by a bite of a female mosquito of the genus Plasmodium. The four Plasmodium species that cause malaria are P. falciparum being the most dangerous, P. vivax, P. ovale, P. malariae, and sometimes caused by monkey malaria parasite, P. knowlesi which is common in Southeast Asia.
At first the fevers appears at random, but may become periodic with time. For P. vivax and P. ovale it occurs at 48-hour intervals, with P. malariae at 72-hour intervals. While P. falciparum usually does not cause a periodic fever.
Commonly Prescribed Drugs
Quinine antibiotic (tetracycline, clindamycin, doxycycline, erythromycin) primaquine
Doxycycline, tetracycline: Should not be used by pregnant women or children younger than 8 years old.
Primaquine: contraindicated in patients with G6PD deficiency.